| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Ligand | BDBM50100712 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.98±n/a nM |
|---|
| Comments | PDSP_4116 |
|---|
| Citation |  Xiao, Y; Kellar, KJ The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells. J Pharmacol Exp Ther310:98-107 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Name: | Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Synonyms: | ACHA3_RAT | Acra3 | Chrna3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56995.52 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P04757 |
|---|
| Residue: | 499 |
|---|
| Sequence: | MGVVLLPPPLSMLMLVLMLLPAASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEV
SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNN
ADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK
IDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTI
NLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGE
YLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSGEGDT
PKTRTFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSE
SVNAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILV
CILGTAGLFLQPLMARDDT
|
|
|
|---|
| BDBM50100712 |
|---|
| n/a |
|---|
| Name | BDBM50100712 |
|---|
| Synonyms: | 2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | CHEMBL54586 | Epibatidine-I,(+/-) | IPH |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H13IN2 |
|---|
| Mol. Mass. | 300.1388 |
|---|
| SMILES | Ic1ccc(cn1)C1CC2CCC1N2 |THB:4:7:13:11.10| |
|---|
| Structure | 
|
|---|
Search and Browse
