Reaction Details |
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Target | P2X purinoceptor 3 |
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Ligand | BDBM50023910 |
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Substrate/Competitor | n/a |
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Ki | 2610±n/a nM |
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Comments | PDSP_4066 |
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Citation | Jarvis, MF; Bianchi, B; Uchic, JT; Cartmell, J; Lee, CH; Williams, M; Faltynek, C [3H]A-317491, a novel high-affinity non-nucleotide antagonist that specifically labels human P2X2/3 and P2X3 receptors. J Pharmacol Exp Ther310:407-16 (2004) [PubMed] Article |
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More Info.: | Get all data from this article |
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P2X purinoceptor 3 |
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Name: | P2X purinoceptor 3 |
Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa |
Type: | Protein |
Mol. Mass.: | 44292.02 |
Organism: | Homo sapiens (Human) |
Description: | P56373 |
Residue: | 397 |
Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
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BDBM50023910 |
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n/a |
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Name | BDBM50023910 |
Synonyms: | ({[({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | 1-(3,4-dihydroxy-5-triphosphoryloxymethyltetrahydro-2-furanyl)-1,2,3,4-tetrahydro-2,4-pyrimidinedione | 5-azidouridine-5'-triphosphate derivative | UTP | Uridine triphosphate (UTP) |
Type | Small organic molecule |
Emp. Form. | C9H15N2O15P3 |
Mol. Mass. | 484.1411 |
SMILES | OC1C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)OC(C1O)n1ccc(=O)[nH]c1=O |
Structure |
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