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TargetP2X purinoceptor 2
LigandBDBM50000029
Substrate/Competitorn/a
Ki 854±n/a nM
CommentsPDSP_3349
Citation Jarvis MFBianchi BUchic JTCartmell JLee CHWilliams MFaltynek C [3H]A-317491, a novel high-affinity non-nucleotide antagonist that specifically labels human P2X2/3 and P2X3 receptors. J Pharmacol Exp Ther 310:407-16 (2004) [PubMed]  Article
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P2X purinoceptor 2
Name:P2X purinoceptor 2
Synonyms:ATP receptor | P2RX2 | P2X2 | Purinergic receptor | PurinergicP2X2/3
Type:Enzyme Catalytic Domain
Mol. Mass.:51765.18
Organism:Homo sapiens (Human)
Description:PurinergicP2X2/3 0 HUMAN::Q9UBL9
Residue:471
Sequence:
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG
QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
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  Blast E-value cutoff:
BDBM50000029
n/a
NameBDBM50000029
Synonyms:4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8-trisulfo-naphthalen-1-ylcarbamoyl)-phenylcarbamoyl]-phenyl}-ureido)-benzoylamino]-benzoylamino}-naphthalene-1,3,5-trisulfonic acid; hexa-kis Sodium salt | 5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino)]tris[1,3-benzenesulfonate analogue | CHEMBL265502 | SURAMIN HEXASODIUM | suramin | suramin Na
TypeSmall organic molecule
Emp. Form.C51H34N6O23S6
Mol. Mass.1291.235
SMILESCc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O
Structure
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