| Reaction Details |
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 | Report a problem with these data |
| Target | Hrh3 protein |
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| Ligand | BDBM22914 |
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| Substrate/Competitor | n/a |
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| Ki | 3.21±n/a nM |
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| Comments | PDSP_1847 |
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| Citation |  Hancock, AA; Bennani, YL; Bush, EN; Esbenshade, TA; Faghih, R; Fox, GB; Jacobson, P; Knourek-Segel, V; Krueger, KM; Nuss, ME; Pan, JB; Shapiro, R; Witte, DG; Yao, BB Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist. Eur J Pharmacol487:183-97 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Hrh3 protein |
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| Name: | Hrh3 protein |
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| Synonyms: | HISTAMINE H3 | HRH3 | Hrh3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37860.96 |
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| Organism: | RAT |
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| Description: | Q5PPG3 |
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| Residue: | 344 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRF
RLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
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| BDBM22914 |
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| n/a |
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| Name | BDBM22914 |
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| Synonyms: | CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide | Thioperamide | US11622967, Compound Thioperamide |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N4S |
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| Mol. Mass. | 292.443 |
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| SMILES | S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 |
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| Structure | 
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