| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM86523 |
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| Substrate/Competitor | n/a |
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| Ki | 1.78±n/a nM |
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| Comments | PDSP_1209 |
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| Citation |  Knight, AR; Misra, A; Quirk, K; Benwell, K; Revell, D; Kennett, G; Bickerdike, M Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn Schmiedebergs Arch Pharmacol370:114-23 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51836.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28335 |
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| Residue: | 458 |
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| Sequence: | MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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| BDBM86523 |
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| n/a |
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| Name | BDBM86523 |
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| Synonyms: | CAS_17692-51-2 | METERGOLINE | NSC_28693 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3O2 |
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| Mol. Mass. | 403.5167 |
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| SMILES | CN1CC(CNC(=O)OCc2ccccc2)CC2C1Cc1cn(C)c3cccc2c13 |
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| Structure | 
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