| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-5 |
|---|
| Ligand | BDBM82546 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 969±n/a nM |
|---|
| Comments | PDSP_1165 |
|---|
| Citation |  Grinevich, VP; Letchworth, SR; Lindenberger, KA; Menager, J; Mary, V; Sadieva, KA; Buhlman, LM; Bohme, GA; Pradier, L; Benavides, J; Lukas, RJ; Bencherif, M Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit. J Pharmacol Exp Ther312:619-26 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Neuronal acetylcholine receptor subunit alpha-5 |
|---|
| Name: | Neuronal acetylcholine receptor subunit alpha-5 |
|---|
| Synonyms: | ACHA5_RAT | Acra5 | Cholinergic, Nicotinic Alpha6Beta3Beta4Alpha5 | Chrna5 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51875.01 |
|---|
| Organism: | RAT |
|---|
| Description: | Cholinergic, Nicotinic Alpha6Beta3Beta4Alpha5 0 RAT::P20420 |
|---|
| Residue: | 452 |
|---|
| Sequence: | MVQLLAGRWRPTGARRGTRGGLPELSSAAKHEDSLFRDLFEDYERWVRPVEHLSDKIKIK
FGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKIIRVPSDSLWIPDIVL
FDNADGRFEGASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDG
SQVDIILEDQDVDRTDFFDNGEWEIMSAMGSKGNRTDSCCWYPYITYSFVIKRLPLFYTL
FLIIPCIGLSFLTVVVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGE
YLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHADRYFT
QREEAESGAGPKSRNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFL
LVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK
|
|
|
|---|
| BDBM82546 |
|---|
| n/a |
|---|
| Name | BDBM82546 |
|---|
| Synonyms: | CAS_14721-69-8 | MCC | N-methylcarbamylcholine | NMCC |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H17N2O2 |
|---|
| Mol. Mass. | 161.2215 |
|---|
| SMILES | CNC(=O)OCC[N+](C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
