| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
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| Ligand | BDBM81780 |
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| Substrate/Competitor | n/a |
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| Ki | 914±n/a nM |
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| Comments | PDSP_1752 |
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| Citation |  Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology31:265-77 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1B |
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| Name: | 5-hydroxytryptamine receptor 1B |
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| Synonyms: | 5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B |
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| Type: | Protein |
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| Mol. Mass.: | 43173.33 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P28564 |
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| Residue: | 386 |
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| Sequence: | MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATT
LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDF
WLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPP
FFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTP
NKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLI
NPIIYTMSNEDFKQAFHKLIRFKCTG
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| BDBM81780 |
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| n/a |
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| Name | BDBM81780 |
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| Synonyms: | CAS_6438382 | NSC_6438382 | SR 46349B |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21FN2O2 |
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| Mol. Mass. | 328.3806 |
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| SMILES | CN(C)CCON=C(C=Cc1ccc(O)cc1)c1ccccc1F |w:6.5,8.7| |
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| Structure | 
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