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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Rho-associated protein kinase 2 | ||
| Ligand | BDBM86729 | ||
| Substrate/Competitor | n/a | ||
| Ki | 100±n/a nM | ||
| Comments | PDSP_6132 | ||
| Citation |  Braverman, AS; Tibb, AS; Ruggieri, MR M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder. J Pharmacol Exp Ther316:869-74 (2006) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Rho-associated protein kinase 2 | |||
| Name: | Rho-associated protein kinase 2 | ||
| Synonyms: | ROCK2_RAT | Rho Kinase | Rho-associated protein kinase 2 | Rho-associated protein kinase 2 (ROCK II) | Rho-associated, coiled-coil-containing protein kinase 2 | Rho-associated, coiled-coil-containing protein kinase II | RhoA-binding kinase 2 | Rock2 | p150 ROK-alpha | ||
| Type: | Protein | ||
| Mol. Mass.: | 160370.90 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q62868 | ||
| Residue: | 1388 | ||
| Sequence: |
| ||
| BDBM86729 | |||
| n/a | |||
| Name | BDBM86729 | ||
| Synonyms: | (R)-(+)-trans-4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride | CAS_146986-50-7 | Y-27632 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H21N3O | ||
| Mol. Mass. | 247.336 | ||
| SMILES | C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1 |r,wU:6.9,wD:3.2,1.1,(4.6,-3.38,;4.87,-1.86,;6.32,-1.34,;3.69,-.87,;2.92,.46,;1.38,.46,;.61,-.87,;1.38,-2.21,;2.92,-2.21,;-.93,-.87,;-1.7,.46,;-1.7,-2.21,;-3.24,-2.21,;-4.01,-3.54,;-5.55,-3.54,;-6.32,-2.21,;-5.55,-.87,;-4.01,-.87,)| | ||
| Structure | 
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