| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
|---|
| Ligand | BDBM86757 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 6.75±n/a nM |
|---|
| Comments | PDSP_7627 |
|---|
| Citation |  Kumar, JS; Prabhakaran, J; Majo, VJ; Milak, MS; Hsiung, SC; Tamir, H; Simpson, NR; Van Heertum, RL; Mann, JJ; Parsey, RV Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates. Eur J Nucl Med Mol Imaging34:1050-60 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Solute carrier family 22 member 1 |
|---|
| Name: | Solute carrier family 22 member 1 |
|---|
| Synonyms: | OCT1 | S22A1_BOVIN | SLC22A1 | adrenergic Alpha1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 62499.05 |
|---|
| Organism: | BOVINE |
|---|
| Description: | adrenergic Alpha1 0 BOVINE::A7MBE0 |
|---|
| Residue: | 563 |
|---|
| Sequence: | MLTVDDVLEQVGEFGWFQKQTFLILCLLSAAFAPIYVGIVFLAFTPDHRCRSPGVAELSR
RCGWSLAEELNYTVPGPGPESQCLRYEVDWNQSTLGCLDPLASLATNGSPLPLGPCEQGW
VYDTPGSSIVTEFNLVCDDSWKVDLFQSCVNLGFFLGSLGVGYIADRFGRKVCLLATTLT
CASLGVLTAVAPDYTSLLIFRLLQGLVSKGSWTAGYTLITEFVGLGYRRTVAILYQMAFT
VGLVLLSGLAYILPHWRWLQLAVSLPIFLLLFRFWFVPESPRWLLSQKRNTEAIKIMDHI
AQKNGKLPPADLKMLSLEEDVTEKLSPSFIDLFRTPNLRKYTFILMYLWFTSSVVYQGLI
MHVGATGGNLYLDFLYSALVEFPAGFIILVTIDRFGRRYPLATSNLAAGLACFLMIFIPH
DLPWLNIMVACVGRMGITIVFQMVCLVNAELFPTFIRNLGMMVCSSLCDLGGVLTPFLVF
RLMEVWQGSPLILFAALGLVAGGMTLLLPETKGVTLPETIEDAENLQRKAKPKENKIYLQ
VQTSELNTQAAERDASQGTAQQK
|
|
|
|---|
| BDBM86757 |
|---|
| n/a |
|---|
| Name | BDBM86757 |
|---|
| Synonyms: | CAS_0 | NSC_11603174 | [11C]MMP |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H27N5O3 |
|---|
| Mol. Mass. | 373.4494 |
|---|
| SMILES | COc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
