| Reaction Details |
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 | Report a problem with these data |
| Target | GTP-binding nuclear protein GSP1/CNR1 |
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| Ligand | BDBM21278 |
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| Substrate/Competitor | n/a |
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| Ki | 1.98±n/a nM |
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| Comments | PDSP_7040 |
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| Citation |  Wang, H; Duffy, RA; Boykow, GC; Chackalamannil, S; Madison, VS Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model. J Med Chem51:2439-46 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| GTP-binding nuclear protein GSP1/CNR1 |
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| Name: | GTP-binding nuclear protein GSP1/CNR1 |
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| Synonyms: | CANNABINOID CB1 | CNR1 | CST17 | GSP1 | GSP1_YEAST | GTP-binding nuclear protein GSP1/CNR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24810.06 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | CANNABINOID CB1 CNR1 0::P32835 |
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| Residue: | 219 |
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| Sequence: | MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGE
IKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIV
LCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVA
SPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL
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| BDBM21278 |
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| n/a |
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| Name | BDBM21278 |
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| Synonyms: | 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide | Acomplia | CHEMBL111 | CHEMBL558598 | RIMONABANT HYDROCHLORIDE | Rimonabant | SR 141716A | SR141716 | SR141716A | [3H]Rimonabant | [3H]SR141716A |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21Cl3N4O |
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| Mol. Mass. | 463.787 |
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| SMILES | Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 |
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| Structure | 
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