| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM26190 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| pH | 6.8±0 |
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| Temperature | 298.15±0 K |
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| IC50 | 1.882e+5±n/a nM |
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| Citation |  Liu, SH; Chu, IM; Pan, IH Effects of hydroxybenzyl alcohols on melanogenesis in melanocyte-keratinocyte co-culture and monolayer culture of melanocytes. J Enzyme Inhib Med Chem23:526-34 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | TYRO_MOUSE | Tyr |
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| Type: | Protein |
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| Mol. Mass.: | 60600.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 533 |
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| Sequence: | MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILL
SSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIR
RNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMH
YYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRD
AENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRN
PGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQS
SMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGH
NRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLG
AALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
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| BDBM26190 |
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| n/a |
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| Name | BDBM26190 |
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| Synonyms: | 1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene | CHEMBL537 | Hydroquinone (9) | Hydroquinone, HQ | benzene-1,4-diol | phenol derivative, 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H6O2 |
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| Mol. Mass. | 110.1106 |
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| SMILES | Oc1ccc(O)cc1 |
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| Structure | 
|
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