| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase D1 |
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| Ligand | BDBM87183 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cellular PLD1 concentration response |
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| IC50 | 2±n/a nM |
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| Citation |  PubChem, PC Cellular PLD1 concentration response PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase D1 |
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| Name: | Phospholipase D1 |
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| Synonyms: | Choline phosphatase 1 | PLD 1 | PLD1 | PLD1_HUMAN | Phosphatidylcholine-hydrolyzing phospholipase D1 | Phospholipase D (PLD) | Phospholipase D1 | Phospholipase D1 (PLD1) | Phospholipase D2 (PLD2) | hPLD1 |
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| Type: | Protein |
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| Mol. Mass.: | 124219.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13393 |
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| Residue: | 1074 |
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| Sequence: | MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
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| BDBM87183 |
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| n/a |
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| Name | BDBM87183 |
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| Synonyms: | N-[(1R)-2-[4-(5-chloro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid | N-[(2R)-1-[4-(5-chloranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | N-[(2R)-1-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]propan-2-yl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid | N-[(2R)-1-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid | VU0364737-1 | cid_53470048 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26ClN5O2 |
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| Mol. Mass. | 451.949 |
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| SMILES | C[C@H](CN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O)NC(=O)c1cc2ccccc2[nH]1 |
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| Structure | 
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