Reaction Details |
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Target | Tegument protein VP16 |
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Ligand | BDBM57102 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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IC50 | >1328±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Tegument protein VP16 |
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Name: | Tegument protein VP16 |
Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
Type: | PROTEIN |
Mol. Mass.: | 54325.13 |
Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
Description: | EBI_100271 |
Residue: | 490 |
Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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BDBM57102 |
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n/a |
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Name | BDBM57102 |
Synonyms: | MLS000541562 | N-cyclohexyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine | N-cyclohexyl-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine | SMR000126420 | cid_6404647 | cyclohexyl-[6-phenyl-3-(2-pyridyl)-1,2,4-triazin-5-yl]amine |
Type | Small organic molecule |
Emp. Form. | C20H21N5 |
Mol. Mass. | 331.4142 |
SMILES | C1CCC(CC1)Nc1nc(nnc1-c1ccccc1)-c1ccccn1 |
Structure |
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