| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tegument protein VP16 |
|---|
| Ligand | BDBM76171 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
|---|
| IC50 | 4823±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tegument protein VP16 |
|---|
| Name: | Tegument protein VP16 |
|---|
| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54325.13 |
|---|
| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
|---|
| Description: | EBI_100271 |
|---|
| Residue: | 490 |
|---|
| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
|
|
|
|---|
| BDBM76171 |
|---|
| n/a |
|---|
| Name | BDBM76171 |
|---|
| Synonyms: | (2E,6E)-2,6-bis(3-chloro-5-ethoxy-4-hydroxy-benzylidene)cyclohexanone | (2E,6E)-2,6-bis[(3-chloranyl-5-ethoxy-4-oxidanyl-phenyl)methylidene]cyclohexan-1-one | (2E,6E)-2,6-bis[(3-chloro-5-ethoxy-4-hydroxyphenyl)methylidene]-1-cyclohexanone | (2E,6E)-2,6-bis[(3-chloro-5-ethoxy-4-hydroxyphenyl)methylidene]cyclohexan-1-one | 2,6-bis(3-chloro-5-ethoxy-4-hydroxybenzylidene)cyclohexanone | MLS000540055 | SMR000162201 | cid_1751796 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H24Cl2O5 |
|---|
| Mol. Mass. | 463.35 |
|---|
| SMILES | CCOc1cc(\C=C2/CCC\C(=C/c3cc(Cl)c(O)c(OCC)c3)C2=O)cc(Cl)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
