Reaction Details |
| Report a problem with these data |
Target | Tegument protein VP16 |
---|
Ligand | BDBM67919 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
---|
IC50 | 7956±n/a nM |
---|
Citation | PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Tegument protein VP16 |
---|
Name: | Tegument protein VP16 |
Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
Type: | PROTEIN |
Mol. Mass.: | 54325.13 |
Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
Description: | EBI_100271 |
Residue: | 490 |
Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
|
|
|
BDBM67919 |
---|
n/a |
---|
Name | BDBM67919 |
Synonyms: | 1-[4-(2,4-Dichloro-benzyloxy)-phenyl]-3-phenyl-thiourea | 1-[4-(2,4-dichlorobenzyl)oxyphenyl]-3-phenyl-thiourea | 1-[4-[(2,4-dichlorophenyl)methoxy]phenyl]-3-phenyl-thiourea | 1-[4-[(2,4-dichlorophenyl)methoxy]phenyl]-3-phenylthiourea | MLS000555361 | SMR000172461 | cid_1143231 |
Type | Small organic molecule |
Emp. Form. | C20H16Cl2N2OS |
Mol. Mass. | 403.325 |
SMILES | Clc1ccc(COc2ccc(NC(=S)Nc3ccccc3)cc2)c(Cl)c1 |
Structure |
|