Reaction Details |
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Target | Tegument protein VP16 |
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Ligand | BDBM77529 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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IC50 | 7920±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Tegument protein VP16 |
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Name: | Tegument protein VP16 |
Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
Type: | PROTEIN |
Mol. Mass.: | 54325.13 |
Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
Description: | EBI_100271 |
Residue: | 490 |
Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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BDBM77529 |
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n/a |
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Name | BDBM77529 |
Synonyms: | MLS000548411 | N-[1,3-benzodioxol-5-yl-(5-chloranyl-8-oxidanyl-quinolin-7-yl)methyl]butanamide | N-[1,3-benzodioxol-5-yl-(5-chloro-8-hydroxy-7-quinolinyl)methyl]butanamide | N-[1,3-benzodioxol-5-yl-(5-chloro-8-hydroxy-7-quinolyl)methyl]butyramide | N-[1,3-benzodioxol-5-yl-(5-chloro-8-hydroxyquinolin-7-yl)methyl]butanamide | N-[Benzo[1,3]dioxol-5-yl-(5-chloro-8-hydroxy-quinolin-7-yl)-methyl]-butyramide | SMR000172091 | cid_3138755 |
Type | Small organic molecule |
Emp. Form. | C21H19ClN2O4 |
Mol. Mass. | 398.84 |
SMILES | CCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O |
Structure |
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