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TargetTegument protein VP16
LigandBDBM87274
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
IC50 6590±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
Tegument protein VP16
Name:Tegument protein VP16
Synonyms:Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:PROTEIN
Mol. Mass.:54325.13
Organism:Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:EBI_100271
Residue:490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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  Blast E-value cutoff:
BDBM87274
n/a
NameBDBM87274
Synonyms:2-(N-(2-chloro-1-oxoethyl)-4-methoxyanilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-(N-(2-chloroacetyl)-4-methoxy-anilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-(N-(2-chloroacetyl)-4-methoxyanilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-[(chloroacetyl)(4-methoxyphenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-[2-chloranylethanoyl-(4-methoxyphenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)ethanamide | MLS000583961 | SMR000206947 | cid_12004951
TypeSmall organic molecule
Emp. Form.C24H29ClN2O4
Mol. Mass.444.951
SMILESCOc1ccc(cc1)C(N(C(=O)CCl)c1ccc(OC)cc1)C(=O)NC1CCCCC1
Structure
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