| Reaction Details |
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 | Report a problem with these data |
| Target | Tegument protein VP16 |
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| Ligand | BDBM87278 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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| IC50 | 6449±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tegument protein VP16 |
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| Name: | Tegument protein VP16 |
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| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.13 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | EBI_100271 |
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| Residue: | 490 |
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| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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| BDBM87278 |
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| n/a |
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| Name | BDBM87278 |
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| Synonyms: | 5-Bromo-nicotinic acid [1-(5-nitro-thiophen-2-yl)-meth-(Z)-ylidene]-hydrazide | 5-bromanyl-N-[(Z)-(5-nitrothiophen-2-yl)methylideneamino]pyridine-3-carboxamide | 5-bromo-N-[(Z)-(5-nitro-2-thienyl)methyleneamino]nicotinamide | 5-bromo-N-[(Z)-(5-nitro-2-thiophenyl)methylideneamino]-3-pyridinecarboxamide | 5-bromo-N-[(Z)-(5-nitrothiophen-2-yl)methylideneamino]pyridine-3-carboxamide | MLS000592134 | SMR000218360 | cid_5613214 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H7BrN4O3S |
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| Mol. Mass. | 355.167 |
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| SMILES | [O-][N+](=O)c1ccc(\C=N/NC(=O)c2cncc(Br)c2)s1 |
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| Structure | 
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