| Reaction Details |
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 | Report a problem with these data |
| Target | Tegument protein VP16 |
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| Ligand | BDBM41953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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| IC50 | 7551±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tegument protein VP16 |
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| Name: | Tegument protein VP16 |
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| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.13 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | EBI_100271 |
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| Residue: | 490 |
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| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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| BDBM41953 |
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| n/a |
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| Name | BDBM41953 |
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| Synonyms: | 4-(3,5-dimethylpiperidin-1-yl)sulfonyl-N'-(4-methyl-1,3-benzothiazol-2-yl)benzohydrazide | 4-(3,5-dimethylpiperidino)sulfonyl-N'-(4-methyl-1,3-benzothiazol-2-yl)benzohydrazide | 4-[(3,5-dimethyl-1-piperidinyl)sulfonyl]-N'-(4-methyl-1,3-benzothiazol-2-yl)benzohydrazide | MLS000696648 | SMR000235764 | cid_12006167 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N4O3S2 |
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| Mol. Mass. | 458.597 |
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| SMILES | CC1CC(C)CN(C1)S(=O)(=O)c1ccc(cc1)C(=O)NNc1nc2c(C)cccc2s1 |
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| Structure | 
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