Ki Summary

Reaction Details

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Target

Tegument protein VP16

Ligand

BDBM87295

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)

IC50

6448±n/a nM

Citation

PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tegument protein VP16

Name:

Tegument protein VP16

Synonyms:

Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16

Type:

PROTEIN

Mol. Mass.:

54325.13

Organism:

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)

Description:

EBI_100271

Residue:

490

Sequence:

MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG

BDBM87295

n/a

Name

BDBM87295

Synonyms:

(4-methoxyphenyl)-(3-nitro-4-pyridyl)amine | MLS000718038 | N-(4-methoxyphenyl)-3-nitro-4-pyridinamine | N-(4-methoxyphenyl)-3-nitro-pyridin-4-amine | N-(4-methoxyphenyl)-3-nitropyridin-4-amine | SMR000279806 | cid_2944858

Type

Small organic molecule

Emp. Form.

C12H11N3O3

Mol. Mass.

245.234

SMILES

COc1ccc(Nc2ccncc2[N+]([O-])=O)cc1

Structure