Reaction Details |
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Target | Tegument protein VP16 |
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Ligand | BDBM87300 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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IC50 | 7964±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Tegument protein VP16 |
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Name: | Tegument protein VP16 |
Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
Type: | PROTEIN |
Mol. Mass.: | 54325.13 |
Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
Description: | EBI_100271 |
Residue: | 490 |
Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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BDBM87300 |
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n/a |
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Name | BDBM87300 |
Synonyms: | (1-ethylimidazol-2-yl)methyl-[[5-(3-fluoro-4-methoxy-phenyl)-1H-pyrazol-4-yl]methyl]-methyl-amine | 1-(1-ethyl-1H-imidazol-2-yl)-N-{[3-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]methyl}-N-methylmethanamine | MLS000734898 | N-[(1-ethyl-2-imidazolyl)methyl]-1-[5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]-N-methylmethanamine | N-[(1-ethylimidazol-2-yl)methyl]-1-[5-(3-fluoranyl-4-methoxy-phenyl)-1H-pyrazol-4-yl]-N-methyl-methanamine | N-[(1-ethylimidazol-2-yl)methyl]-1-[5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]-N-methylmethanamine | SMR000315814 | cid_16191488 |
Type | Small organic molecule |
Emp. Form. | C18H22FN5O |
Mol. Mass. | 343.3986 |
SMILES | CCn1ccnc1CN(C)Cc1c[nH]nc1-c1ccc(OC)c(F)c1 |
Structure |
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