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TargetTegument protein VP16
LigandBDBM87308
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
IC50 7500±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
Tegument protein VP16
Name:Tegument protein VP16
Synonyms:Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:PROTEIN
Mol. Mass.:54325.13
Organism:Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:EBI_100271
Residue:490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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  Blast E-value cutoff:
BDBM87308
n/a
NameBDBM87308
Synonyms:4-[4-(1-benzimidazolyl)phenyl]-2-pyrimidinamine | 4-[4-(1H-1,3-benzimidazol-1-yl)phenyl]-2-pyrimidinylamine | 4-[4-(benzimidazol-1-yl)phenyl]pyrimidin-2-amine | MLS000763405 | SMR000336277 | [4-[4-(benzimidazol-1-yl)phenyl]pyrimidin-2-yl]amine | cid_1477777
TypeSmall organic molecule
Emp. Form.C17H13N5
Mol. Mass.287.3186
SMILESNc1nccc(n1)-c1ccc(cc1)-n1cnc2ccccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: