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TargetTegument protein VP16
LigandBDBM63792
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
IC50 4769±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
Tegument protein VP16
Name:Tegument protein VP16
Synonyms:Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:PROTEIN
Mol. Mass.:54325.13
Organism:Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:EBI_100271
Residue:490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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  Blast E-value cutoff:
BDBM63792
n/a
NameBDBM63792
Synonyms:2-(2,4-Dichloro-phenylamino)-4-oxo-4-phenyl-butyric acid | 2-(2,4-dichloroanilino)-4-keto-4-phenyl-butyric acid | 2-(2,4-dichloroanilino)-4-oxo-4-phenylbutanoic acid | 2-[(2,4-dichlorophenyl)amino]-4-oxidanylidene-4-phenyl-butanoic acid | MLS000766654 | SMR000414629 | cid_3762447
TypeSmall organic molecule
Emp. Form.C16H13Cl2NO3
Mol. Mass.338.185
SMILESOC(=O)C(CC(=O)c1ccccc1)Nc1ccc(Cl)cc1Cl
Structure
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