Ki Summary

Reaction Details

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Target

Tegument protein VP16

Ligand

BDBM87322

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)

IC50

>3988±n/a nM

Citation

PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tegument protein VP16

Name:

Tegument protein VP16

Synonyms:

Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16

Type:

PROTEIN

Mol. Mass.:

54325.13

Organism:

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)

Description:

EBI_100271

Residue:

490

Sequence:

MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG

BDBM87322

n/a

Name

BDBM87322

Synonyms:

1H-benzimidazol-2-yl-[(E)-8-quinolylmethyleneamino]amine | MLS000758870 | N-(1H-Benzoimidazol-2-yl)-N'-[1-quinolin-8-yl-meth-(E)-ylidene]-hydrazine | N-[(E)-8-quinolinylmethylideneamino]-1H-benzimidazol-2-amine | N-[(E)-quinolin-8-ylmethylideneamino]-1H-benzimidazol-2-amine | SMR000440095 | cid_9629711

Type

Small organic molecule

Emp. Form.

C17H13N5

Mol. Mass.

287.3186

SMILES

C(N=Nc1nc2ccccc2[nH]1)c1cccc2cccnc12 |w:2.2|

Structure