| Reaction Details |
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 | Report a problem with these data |
| Target | Tegument protein VP16 |
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| Ligand | BDBM47479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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| IC50 | 5007±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tegument protein VP16 |
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| Name: | Tegument protein VP16 |
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| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.13 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | EBI_100271 |
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| Residue: | 490 |
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| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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| BDBM47479 |
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| n/a |
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| Name | BDBM47479 |
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| Synonyms: | 6-amino-5-[1-(2-fluoro-6-methoxy-phenyl)-2-nitro-ethyl]-1,3-dimethyl-pyrimidine-2,4-quinone | 6-amino-5-[1-(2-fluoro-6-methoxyphenyl)-2-nitroethyl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione | 6-amino-5-[1-(2-fluoro-6-methoxyphenyl)-2-nitroethyl]-1,3-dimethylpyrimidine-2,4-dione | 6-azanyl-5-[1-(2-fluoranyl-6-methoxy-phenyl)-2-nitro-ethyl]-1,3-dimethyl-pyrimidine-2,4-dione | MLS000861865 | SMR000460649 | cid_2732795 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17FN4O5 |
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| Mol. Mass. | 352.3177 |
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| SMILES | COc1cccc(F)c1C(C[N+]([O-])=O)c1c(N)n(C)c(=O)n(C)c1=O |
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| Structure | 
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