Reaction Details |
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Target | Tegument protein VP16 |
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Ligand | BDBM34264 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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IC50 | 4277±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Tegument protein VP16 |
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Name: | Tegument protein VP16 |
Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
Type: | PROTEIN |
Mol. Mass.: | 54325.13 |
Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
Description: | EBI_100271 |
Residue: | 490 |
Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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BDBM34264 |
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n/a |
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Name | BDBM34264 |
Synonyms: | 2-(6-bromo-4,5-dihydroxy-3-p-toluoyl-benzofuran-7-yl)-3-keto-butyric acid ethyl ester | 2-[6-bromo-4,5-dihydroxy-3-[(4-methylphenyl)-oxomethyl]-7-benzofuranyl]-3-oxobutanoic acid ethyl ester | MLS000040280 | SMR000044279 | cid_663373 | ethyl 2-[6-bromanyl-3-(4-methylphenyl)carbonyl-4,5-bis(oxidanyl)-1-benzofuran-7-yl]-3-oxidanylidene-butanoate | ethyl 2-[6-bromo-4,5-dihydroxy-3-(4-methylbenzoyl)-1-benzofuran-7-yl]-3-oxobutanoate |
Type | Small organic molecule |
Emp. Form. | C22H19BrO7 |
Mol. Mass. | 475.286 |
SMILES | CCOC(=O)C(C(C)=O)c1c(Br)c(O)c(O)c2c(coc12)C(=O)c1ccc(C)cc1 |
Structure |
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