Ki Summary

Reaction Details

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Target

High affinity choline transporter 1

Ligand

BDBM87580

Substrate/Competitor

n/a

Meas. Tech.

JHICC_CHT_Inh_3H uptake_CRC

IC50

8421.798897±n/a nM

Citation

PubChem, PC JHICC_CHT_Inh_3H uptake_CRC PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

High affinity choline transporter 1

Name:

High affinity choline transporter 1

Synonyms:

CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1

Type:

PROTEIN

Mol. Mass.:

63194.33

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1464247

Residue:

580

Sequence:

MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ

BDBM87580

n/a

Name

BDBM87580

Synonyms:

3-(benzylsulfamoyl)-N-(4-methylcyclohexyl)benzamide | MLS001071700 | N-(4-methylcyclohexyl)-3-[(phenylmethyl)sulfamoyl]benzamide | SMR000710522 | cid_18106490

Type

Small organic molecule

Emp. Form.

C21H26N2O3S

Mol. Mass.

386.508

SMILES

CC1CCC(CC1)NC(=O)c1cccc(c1)S(=O)(=O)NCc1ccccc1 |(3.08,-8.09,;4.41,-7.32,;4.41,-5.78,;5.75,-5.01,;7.08,-5.78,;7.08,-7.32,;5.75,-8.09,;8.41,-5.01,;8.41,-3.47,;7.08,-2.7,;9.75,-2.7,;11.08,-3.47,;12.42,-2.7,;12.42,-1.16,;11.08,-.39,;9.75,-1.16,;11.08,1.16,;12.62,1.16,;9.54,1.16,;11.08,2.7,;12.42,3.47,;12.42,5.01,;11.08,5.78,;11.08,7.32,;12.42,8.09,;13.75,7.32,;13.75,5.78,)|

Structure