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TargetTyrosine-protein phosphatase non-receptor type 5
LigandBDBM46203
Substrate/Competitorn/a
Meas. Tech.Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50 14500±n/a nM
Citation PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 5
Name:Tyrosine-protein phosphatase non-receptor type 5
Synonyms:PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:Enzyme Catalytic Domain
Mol. Mass.:63510.68
Organism:Homo sapiens (Human)
Description:gi_90652859
Residue:565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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  Blast E-value cutoff:
BDBM46203
n/a
NameBDBM46203
Synonyms:1-(2,6-dichlorophenyl)-3-(2-phenylethyl)thiourea | 1-(2,6-dichlorophenyl)-3-phenethyl-thiourea | 1-[2,6-bis(chloranyl)phenyl]-3-(2-phenylethyl)thiourea | MLS-0307023.0001 | cid_2826665
TypeSmall organic molecule
Emp. Form.C15H14Cl2N2S
Mol. Mass.325.256
SMILESClc1cccc(Cl)c1NC(=S)NCCc1ccccc1
Structure
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