| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 5 |
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| Ligand | BDBM46280 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay |
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| IC50 | 24300±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Tyrosine-protein phosphatase non-receptor type 5 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 5 |
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| Synonyms: | PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 63510.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_90652859 |
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| Residue: | 565 |
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| Sequence: | MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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| BDBM46280 |
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| n/a |
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| Name | BDBM46280 |
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| Synonyms: | 2-[4-[(Z)-[2-(4-ethylanilino)-4-keto-2-thiazolin-5-ylidene]methyl]phenoxy]acetic acid | 2-[4-[(Z)-[2-(4-ethylanilino)-4-oxo-1,3-thiazol-5-ylidene]methyl]phenoxy]acetic acid | 2-[4-[(Z)-[2-(4-ethylanilino)-4-oxo-5-thiazolylidene]methyl]phenoxy]acetic acid | 2-[4-[(Z)-[2-[(4-ethylphenyl)amino]-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]phenoxy]ethanoic acid | MLS-0425605.0001 | cid_5765582 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N2O4S |
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| Mol. Mass. | 382.433 |
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| SMILES | CCc1ccc(NC2=NC(=O)C(S2)=Cc2ccc(OCC(O)=O)cc2)cc1 |w:13.14,t:7| |
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| Structure | 
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