Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM46223 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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IC50 | 331±n/a nM |
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Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM46223 |
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n/a |
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Name | BDBM46223 |
Synonyms: | (4Z)-2-methoxy-4-[piperidin-1-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one | (4Z)-4-[mercapto(1-piperidinyl)methylidene]-2-methoxy-1-cyclohexa-2,5-dienone | (4Z)-4-[mercapto(piperidino)methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | MLS-0103602.0001 | cid_5336454 |
Type | Small organic molecule |
Emp. Form. | C13H17NO2S |
Mol. Mass. | 251.345 |
SMILES | COc1cc(ccc1O)C(=S)N1CCCCC1 |
Structure |
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