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TargetHigh affinity choline transporter 1
LigandBDBM77164
Substrate/Competitorn/a
Meas. Tech.Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50 14470±n/a nM
Citation PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
High affinity choline transporter 1
Name:High affinity choline transporter 1
Synonyms:CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:PROTEIN
Mol. Mass.:63194.33
Organism:Homo sapiens (Human)
Description:ChEMBL_1464247
Residue:580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
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  Blast E-value cutoff:
BDBM77164
n/a
NameBDBM77164
Synonyms:1-(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)-1-(4-fluorophenyl)-N-(furan-2-ylmethyl)-N-(oxolan-2-ylmethyl)methanamine | 1-(1-cyclopentyl-5-tetrazolyl)-1-(4-fluorophenyl)-N-(2-furanylmethyl)-N-(2-oxolanylmethyl)methanamine | 1-(1-cyclopentyltetrazol-5-yl)-1-(4-fluorophenyl)-N-(furan-2-ylmethyl)-N-(oxolan-2-ylmethyl)methanamine | MLS000529105 | SMR000121580 | [(1-Cyclopentyl-1H-tetrazol-5-yl)-(4-fluoro-phenyl)-methyl]-furan-2-ylmethyl-(tetrahydro-furan-2-ylmethyl)-amine | [(1-cyclopentyltetrazol-5-yl)-(4-fluorophenyl)methyl]-(2-furfuryl)-(tetrahydrofurfuryl)amine | cid_3193712
TypeSmall organic molecule
Emp. Form.C23H28FN5O2
Mol. Mass.425.4991
SMILESFc1ccc(cc1)C(N(CC1CCCO1)Cc1ccco1)c1nnnn1C1CCCC1
Structure
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