| Reaction Details |
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 | Report a problem with these data |
| Target | High affinity choline transporter 1 |
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| Ligand | BDBM78811 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC |
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| EC50 | 22020±n/a nM |
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| Citation |  PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| High affinity choline transporter 1 |
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| Name: | High affinity choline transporter 1 |
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| Synonyms: | CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63194.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1464247 |
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| Residue: | 580 |
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| Sequence: | MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
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| BDBM78811 |
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| n/a |
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| Name | BDBM78811 |
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| Synonyms: | 3-cyclohexyl-N-[2-[(3S,6S)-6-[(4-methoxyphenyl)methyl]-3-(phenylmethyl)-2,3,5,6-tetrahydroimidazo[1,2-a]imidazol-7-yl]ethyl]propanamide | MLS000697877 | N-[2-[(3S,6S)-3-benzyl-6-[(4-methoxyphenyl)methyl]-2,3,5,6-tetrahydroimidazo[1,2-a]imidazol-7-yl]ethyl]-3-cyclohexylpropanamide | N-[2-[(3S,6S)-3-benzyl-6-p-anisyl-2,3,5,6-tetrahydroimidaz[1,2-a]imidazol-7-yl]ethyl]-3-cyclohexyl-propionamide | SMR000386399 | cid_16195624 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H42N4O2 |
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| Mol. Mass. | 502.6908 |
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| SMILES | COc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN=C3N2CCNC(=O)CCC2CCCCC2)cc1 |c:20| |
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| Structure | 
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