Ki Summary

Reaction Details

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Target

High affinity choline transporter 1

Ligand

BDBM89162

Substrate/Competitor

n/a

Meas. Tech.

Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC

EC50

20900±n/a nM

Citation

PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

High affinity choline transporter 1

Name:

High affinity choline transporter 1

Synonyms:

CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1

Type:

PROTEIN

Mol. Mass.:

63194.33

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1464247

Residue:

580

Sequence:

MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ

BDBM89162

n/a

Name

BDBM89162

Synonyms:

(3,4-Dimethoxy-benzyl)-[3-(4-fluoro-phenyl)-3-(4-methoxy-phenyl)-propyl]-amine | MLS000333637 | N-[(3,4-dimethoxyphenyl)methyl]-3-(4-fluorophenyl)-3-(4-methoxyphenyl)-1-propanamine | N-[(3,4-dimethoxyphenyl)methyl]-3-(4-fluorophenyl)-3-(4-methoxyphenyl)propan-1-amine | SMR000437778 | [3-(4-fluorophenyl)-3-(4-methoxyphenyl)propyl]-veratryl-amine | cid_4422455

Type

Small organic molecule

Emp. Form.

C25H28FNO3

Mol. Mass.

409.4931

SMILES

COc1ccc(cc1)C(CCNCc1ccc(OC)c(OC)c1)c1ccc(F)cc1

Structure