| Reaction Details |
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 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
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| Ligand | BDBM89265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay |
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| IC50 | 1510±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Zinc finger protein GLI1 |
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| Name: | Zinc finger protein GLI1 |
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| Synonyms: | GLI1_MOUSE | Gli | Gli1 | Glioma-associated oncogene homolog |
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| Type: | PROTEIN |
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| Mol. Mass.: | 118579.34 |
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| Organism: | Mus musculus |
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| Description: | EBI_101259 |
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| Residue: | 1111 |
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| Sequence: | MFNPMTPPQVNSYSEPCCLRPLHSQGVPSMGTEGLSGLPFCHQANFMSGSQGYGAARETS
SCTEGSLFPPPPPPRSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSP
GGSYGHLSIGTMSPSLGFPPQMSHQKGTSPPYGVQPCVPHDSTRGSMMLHPQSRGPRATC
QLKSELDMMVGKCPEDPLEGDMSSPNSTGTQDHLLGMLDGREDLEREEKPEPESVYETDC
RWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTG
EKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHS
NEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAQPLSTVEPKRE
REGGSGREESRLTVPESAMPQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDL
SSLDEGPCVSATGLSTLRRLENLRLDQLHQLRPIGSRGLKLPSLTHAGAPVSRRLGPPVS
LDRRSSSSSSMSSAYTVSRRSSLASPFPPGTPPENGASSLPGLTPAQHYMLRARYASARG
SGTPPTAAHSLDRMGGLSVPPWRSRTEYPGYNPNAGVTRRASDPARAADHPAPARVQRFK
SLGCVHTPPSVATGRNFDPHHPTSVYSPQPPSITENVAMDTRGLQEEPEVGTSVMGNGLN
PYMDFSSTDTLGYGGPEGTAAEPYEARGPGSLPLGPGPPTNYGPGHCAQQVSYPDPTPEN
WGEFPSHAGVYPSNKAPGAAYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSE
GSPGPQPLFSHHPQLPQPQYPQSGPYPQPPHGYLSTEPRLGLNFNPSSSHSTGQLKAQLV
CNYVQSQQELLWEGRNRGGLPNQELPYQSPKFLGGSQVSQSPAKTPAAAAAAYGSGFAPA
SANHKSGSYPAPSPCHETFTVGVNRPSHRPAAPPRLLPPLSPCYGPLKVGDTNPSCGHPE
VGRLGAGPALYPPPEGQVCNALDSLDLDNTQLDFVAILDEAQGLSPPLSHEQGDSSKNTP
SPSGPPNMAVGNMSVLLGSLPGETQFLNSSA
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| BDBM89265 |
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| n/a |
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| Name | BDBM89265 |
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| Synonyms: | MLS000580834 | N-(3-Chloro-4-methyl-phenyl)-2-oxo-2-{N'-[1-pyridin-4-yl-eth-(E)-ylidene]-hydrazino}-acetamide | N-(3-chloranyl-4-methyl-phenyl)-N'-[(E)-1-pyridin-4-ylethylideneamino]ethanediamide | N-(3-chloro-4-methyl-phenyl)-N'-[(E)-1-(4-pyridyl)ethylideneamino]oxamide | N-(3-chloro-4-methylphenyl)-N'-[(E)-1-pyridin-4-ylethylideneamino]oxamide | SMR000220297 | cid_9668287 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15ClN4O2 |
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| Mol. Mass. | 330.769 |
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| SMILES | CC(=NNC(=O)C(=O)Nc1ccc(C)c(Cl)c1)c1ccncc1 |w:2.2| |
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| Structure | 
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