| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM59063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 |
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| Temperature | 298.15±n/a K |
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| IC50 | 345±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM59063 |
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| n/a |
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| Name | BDBM59063 |
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| Synonyms: | 4-butyl-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 4-butyl-1-thioxo-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | MLS001172798 | SMR000595763 | US20230365568, Compound 23 | cid_2120114 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14N4OS |
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| Mol. Mass. | 274.341 |
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| SMILES | CCCCn1c2n[nH]c(=S)n2c2ccccc2c1=O |
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| Structure | 
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