| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-5 [D153N] |
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| Ligand | BDBM50289001 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | KLK5 Assay |
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| pH | 8±n/a |
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| Temperature | 310.15±n/a K |
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| Ki | 4500±n/a nM |
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| Comments | extracted |
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| Citation |  Wagberg, F; Leonardsson, G Benzoxazinone derivatives for treatment of skin diseases US Patent US9695194 Publication Date 7/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kallikrein-5 [D153N] |
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| Name: | Kallikrein-5 [D153N] |
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| Synonyms: | KLK-L2 | KLK5 | KLK5_HUMAN | Kallikrein 5 | Kallikrein-5 | Kallikrein-like protein 2 | SCTE | Stratum corneum tryptic enzyme |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32031.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1282456 |
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| Residue: | 293 |
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| Sequence: | MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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| BDBM50289001 |
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| n/a |
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| Name | BDBM50289001 |
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| Synonyms: | 2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazin-4-one | CHEMBL349763 | US9695194, 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12INO4 |
|---|
| Mol. Mass. | 409.1753 |
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| SMILES | COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1I |
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| Structure | 
|
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