| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Ligand | BDBM31756 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 1700±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 23013.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_21955158 |
|---|
| Residue: | 199 |
|---|
| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
|
|
|---|
| BDBM31756 |
|---|
| n/a |
|---|
| Name | BDBM31756 |
|---|
| Synonyms: | 6,7-dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid | MLS-0007635.0001 | cid_646406 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H17NO2 |
|---|
| Mol. Mass. | 243.301 |
|---|
| SMILES | Cc1ccc2C3C=CCC3C(Nc2c1C)C(O)=O |c:6| |
|---|
| Structure | 
|
|---|
Search and Browse
