| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine-binding protein |
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| Ligand | BDBM91619 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. |
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| pH | 7.4±n/a |
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| Temperature | 293.15±n/a K |
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| Ki | 120±n/a nM |
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| Citation |  Yamauchi, JG; Gomez, K; Grimster, N; Dufouil, M; Nemecz, A; Fotsing, JR; Ho, K; Talley, TT; Sharpless, K; Fokin, VV; Taylor, P Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. Mol Pharmacol82:687-699 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine-binding protein |
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| Name: | Acetylcholine-binding protein |
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| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP |
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| Type: | n/a |
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| Mol. Mass.: | 26055.52 |
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| Organism: | Lymnaea stagnalis |
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| Description: | Soluble acetylcholine receptor |
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| Residue: | 229 |
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| Sequence: | MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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| BDBM91619 |
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| n/a |
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| Name | BDBM91619 |
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| Synonyms: | 19q | alpha7 agonists 19q |
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| Type | n/a |
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| Emp. Form. | C19H24F3N4O |
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| Mol. Mass. | 381.4147 |
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| SMILES | C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C(O)(c1ccccc1)C(F)(F)F |THB:10:8:4.5:1| |
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| Structure | 
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