| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine-binding protein |
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| Ligand | BDBM91621 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. |
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| pH | 7.4±n/a |
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| Temperature | 293.15±n/a K |
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| Ki | 40±n/a nM |
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| Citation |  Yamauchi, JG; Gomez, K; Grimster, N; Dufouil, M; Nemecz, A; Fotsing, JR; Ho, K; Talley, TT; Sharpless, K; Fokin, VV; Taylor, P Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. Mol Pharmacol82:687-699 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine-binding protein |
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| Name: | Acetylcholine-binding protein |
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| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP |
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| Type: | n/a |
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| Mol. Mass.: | 26055.52 |
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| Organism: | Lymnaea stagnalis |
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| Description: | Soluble acetylcholine receptor |
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| Residue: | 229 |
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| Sequence: | MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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| BDBM91621 |
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| n/a |
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| Name | BDBM91621 |
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| Synonyms: | 21q | alpha7 agonists 21q |
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| Type | n/a |
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| Emp. Form. | C20H31N6S |
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| Mol. Mass. | 387.565 |
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| SMILES | Cc1cc(C)nc(SCCCc2cn(nn2)[C@H]2C[C@@H]3CC[C@H](C2)[N+]3(C)C)n1 |TLB:13:16:19.20:23| |
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| Structure | 
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