| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 3A |
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| Ligand | BDBM91628 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. |
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| pH | 7.4±n/a |
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| Temperature | 310.15±n/a K |
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| Ki | 5000±n/a nM |
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| Citation |  Yamauchi, JG; Gomez, K; Grimster, N; Dufouil, M; Nemecz, A; Fotsing, JR; Ho, K; Talley, TT; Sharpless, K; Fokin, VV; Taylor, P Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. Mol Pharmacol82:687-699 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 3A |
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| Name: | 5-hydroxytryptamine receptor 3A |
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| Synonyms: | 5-HT-3 | 5-HT3-A | 5-HT3A | 5-HT3A Serotonin Receptor | 5-HT3R | 5-hydroxytryptamine receptor 3 | 5-hydroxytryptamine receptor 3A | 5HT3A_MOUSE | 5ht3 | Htr3 | Htr3a | Serotonin 3 receptor (5HT3) | Serotonin 3a (5-HT3a) receptor | Serotonin receptor 3A | Serotonin-gated ion channel receptor |
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| Type: | n/a |
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| Mol. Mass.: | 56056.00 |
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| Organism: | Mus musculus (house mouse) |
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| Description: | 5HT3A |
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| Residue: | 487 |
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| Sequence: | MRLCIPQVLLALFLSMLTAPGEGSRRRATQEDTTQPALLRLSDHLLANYKKGVRPVRDWR
KPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIW
VPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFT
SWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYV
IIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLP
ATIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCL
GEQPMAHRPPATFQANKTDDCSGSDLLPAMGNHCSHVGGPQDLEKTPRGRGSPLPPPREA
SLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTL
WSIWHYS
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| BDBM91628 |
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| n/a |
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| Name | BDBM91628 |
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| Synonyms: | 13t | alpha7 agonists 13t |
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| Type | n/a |
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| Emp. Form. | C19H24N4O3 |
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| Mol. Mass. | 356.4189 |
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| SMILES | COc1ccc(C=O)c(OCc2cn(nn2)[C@H]2C[C@@H]3CC[C@H](C2)N3C)c1 |TLB:13:16:20.19:23| |
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| Structure | 
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