Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAlpha-(1,3)-fucosyltransferase 7
LigandBDBM50070942
Substrate/Competitorn/a
Meas. Tech.SPA Assay
pH7.3±0
Temperature295.15±0 K
IC50 700±200 nM
Citation Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys425:51-7 (2004) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Alpha-(1,3)-fucosyltransferase 7
Name:Alpha-(1,3)-fucosyltransferase 7
Synonyms:Alpha-(1,3)-fucosyltransferase VII | FUT7 | FUT7_HUMAN | Fucosyltransferase VII | Fuct VII
Type:n/a
Mol. Mass.:39259.56
Organism:Homo sapiens (Human)
Description:Q11130
Residue:342
Sequence:
MNNAGHGPTRRLRGLGVLAGVALLAALWLLWLLGSAPRGTPAPQPTITILVWHWPFTDQP
PELPSDTCTRYGIARCHLSANRSLLASADAVVFHHRELQTRRSHLPLAQRPRGQPWVWAS
MESPSHTHGLSHLRGIFNWVLSYRRDSDIFVPYGRLEPHWGPSPPLPAKSRVAAWVVSNF
QERQLRARLYRQLAPHLRVDVFGRANGRPLCASCLVPTVAQYRFYLSFENSQHRDYITEK
FWRNALVAGTVPVVLGPPRATYEAFVPADAFVHVDDFGSARELAAFLTGMNESRYQRFFA
WRDRLRVRLFTDWRERFCAICDRYPHLPRSQVYEDLEGWFQA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50070942
n/a
NameBDBM50070942
Synonyms:(-)-Epigallocatechin gallate | (-)-Epigallocatechin-3-o-gallate | (-)-epigallocatechin 3-gallate | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | CHEMBL297453 | EGCG | Epigallocatechin 3-gallate | Epigallocatechin monogallate, B | cid_65064
TypeSmall organic molecule
Emp. Form.C22H18O11
Mol. Mass.458.3717
SMILESOc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: