| Reaction Details |
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 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
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| Ligand | BDBM92483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| pH | 7.8±0 |
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| Temperature | 296.15±0 K |
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| IC50 | 644±53 nM |
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| Citation |  Cale, JM; Li, SH; Warnock, M; Su, EJ; North, PR; Sanders, KL; Puscau, MM; Emal, CD; Lawrence, DA Characterization of a novel class of polyphenolic inhibitors of plasminogen activator inhibitor-1. J Biol Chem285:7892-902 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Urokinase-type plasminogen activator |
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| Name: | Urokinase-type plasminogen activator |
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| Synonyms: | Plau | UROK_MOUSE | Urokinase-type plasminogen activator (uPA) |
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| Type: | Enzyme |
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| Mol. Mass.: | 48282.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P06869 |
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| Residue: | 433 |
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| Sequence: | MKVWLASLFLCALVVKNSEGGSVLGAPDESNCGCQNGGVCVSYKYFSRIRRCSCPRKFQG
EHCEIDASKTCYHGNGDSYRGKANTDTKGRPCLAWNAPAVLQKPYNAHRPDAISLGLGKH
NYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCSLSKKPSSSVDQQGFQCGQKALRPRFKI
VGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVY
LGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTI
CLPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINYK
MLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLDW
IQSHIGEEKGLAF
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| BDBM92483 |
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| n/a |
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| Name | BDBM92483 |
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| Synonyms: | CDE-034 | US9120744, CDE-034 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20O10 |
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| Mol. Mass. | 420.3668 |
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| SMILES | Oc1cc(cc(O)c1O)C(=O)O[C@@H]1CCCC[C@H]1OC(=O)c1cc(O)c(O)c(O)c1 |
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| Structure | 
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