| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase CSK |
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| Ligand | BDBM92632 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assay |
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| IC50 | 4e+3±n/a nM |
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| Citation |  Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors. J Biol Chem265:22255-61 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase CSK |
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| Name: | Tyrosine-protein kinase CSK |
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| Synonyms: | C-SRC kinase | C-src tyrosine kinase | CSK | CSK_HUMAN | Protein-tyrosine kinase CYL | Tyrosine Kinase CSK |
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| Type: | Tyrosine-protein kinase |
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| Mol. Mass.: | 50707.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41240 |
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| Residue: | 450 |
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| Sequence: | MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII
PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV
SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ
DEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM
TQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE
AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE
KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK
NCWHLDAAMRPSFLQLREQLEHIKTHELHL
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| BDBM92632 |
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| n/a |
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| Name | BDBM92632 |
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| Synonyms: | Thiazolidine-dione, 1 |
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| Type | Small molecule |
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| Emp. Form. | C11H12N4O2S2 |
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| Mol. Mass. | 296.369 |
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| SMILES | Cn1c(O)csc1=NN=C1SC(=C)C(=O)N1CC=C |w:7.8,9.10| |
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| Structure | 
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