| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase II subunit alpha |
|---|
| Ligand | BDBM92673 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Assay |
|---|
| pH | 7.4±0 |
|---|
| Temperature | 303.15±0 K |
|---|
| IC50 | >3.00e+5±n/a nM |
|---|
| Citation |  Chijiwa, T; Hagiwara, M; Hidaka, H A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. J Biol Chem264:4924-7 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Casein kinase II subunit alpha |
|---|
| Name: | Casein kinase II subunit alpha |
|---|
| Synonyms: | CK II | CK2 | CK2- alpha | CK2A1 | CSK21_HUMAN | CSNK2A1 | Casein kinase 2 | Casein kinase II (CK2) | Casein kinase II alpha/beta | Casein kinase II subunit alpha (CK2 alpha) | Casein kinase II subunit alpha (CK2A1) | Casein kinase II subunit alpha (CK2a I174A) | Casein kinase II subunit alpha (CK2a V66A) | Casein kinase II subunit alpha (CK2a dm V66I174AA) | Casein kinase II subunit alpha (CK2a) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 45151.12 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P68400 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
|
|
|
|---|
| BDBM92673 |
|---|
| n/a |
|---|
| Name | BDBM92673 |
|---|
| Synonyms: | Isoquinolinesulfonamide, CKI-6 |
|---|
| Type | Small molecule |
|---|
| Emp. Form. | C11H13N3O2S |
|---|
| Mol. Mass. | 251.305 |
|---|
| SMILES | NCCNS(=O)(=O)c1cccc2ccncc12 |
|---|
| Structure | 
|
|---|
Search and Browse
