| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-dependent protein kinase type I-alpha regulatory subunit |
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| Ligand | BDBM50011236 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| pH | 7.4±0 |
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| Temperature | 303.15±0 K |
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| IC50 | 3.6e+3±n/a nM |
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| Citation |  Chijiwa, T; Hagiwara, M; Hidaka, H A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. J Biol Chem264:4924-7 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| cAMP-dependent protein kinase type I-alpha regulatory subunit |
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| Name: | cAMP-dependent protein kinase type I-alpha regulatory subunit |
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| Synonyms: | KAP0_BOVIN | PRKAR1A | cAMP-dependent protein kinase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42885.14 |
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| Organism: | Bos taurus |
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| Description: | gi_115496662 |
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| Residue: | 380 |
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| Sequence: | MASGTTASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEE
AKQIQNLQKAGSRADSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKD
YKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGE
MDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLR
KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA
VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGP
CSDILKRNIQQYNSFVSLSV
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| BDBM50011236 |
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| n/a |
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| Name | BDBM50011236 |
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| Synonyms: | CHEMBL344314 | Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide | Isoquinolinesulfonamide, H-9 | N-(2-aminoethyl)isoquinoline-5-sulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13N3O2S |
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| Mol. Mass. | 251.305 |
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| SMILES | NCCNS(=O)(=O)c1cccc2cnccc12 |
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| Structure | 
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