| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acyl-protein thioesterase 1 |
|---|
| Ligand | BDBM26139 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzymatic Protein Activity Assay |
|---|
| IC50 | 2.3e+3± 1e+2 nM |
|---|
| Citation |  Zimmermann, TJ; Bürger, M; Tashiro, E; Kondoh, Y; Martinez, NE; Görmer, K; Rosin-Steiner, S; Shimizu, T; Ozaki, S; Mikoshiba, K; Watanabe, N; Hall, D; Vetter, IR; Osada, H; Hedberg, C; Waldmann, H Boron-based inhibitors of acyl protein thioesterases 1 and 2. Chembiochem14:115-22 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acyl-protein thioesterase 1 |
|---|
| Name: | Acyl-protein thioesterase 1 |
|---|
| Synonyms: | APT-1 | APT1 | Acyl-protein thioesterase 1 (APT1 WT) | LPL-I | LPL1 | LYPA1_HUMAN | LYPLA1 | LysoPLA I | Lysophospholipase 1 | Lysophospholipase I | hAPT1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 24670.33 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O75608 |
|---|
| Residue: | 230 |
|---|
| Sequence: | MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRP
VTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQ
GGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLM
FGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID
|
|
|
|---|
| BDBM26139 |
|---|
| n/a |
|---|
| Name | BDBM26139 |
|---|
| Synonyms: | 1-benzothiophen-2-ylboranediol | 1-benzothiophen-2-ylboronic acid, 18 | CHEMBL34964 | Phenylboronic acid, 11 |
|---|
| Type | n/a |
|---|
| Emp. Form. | C8H7BO2S |
|---|
| Mol. Mass. | 178.016 |
|---|
| SMILES | OB(O)c1cc2ccccc2s1 |
|---|
| Structure | 
|
|---|
Search and Browse
