| Reaction Details |
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 | Report a problem with these data |
| Target | Nicotinamidase |
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| Ligand | BDBM92850 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | GDH-Coupled Nicotinamidase Assay |
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| Ki | 4000±800 nM |
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| Citation |  French, JB; Cen, Y; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism. Biochemistry49:10421-39 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nicotinamidase |
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| Name: | Nicotinamidase |
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| Synonyms: | Nicotinamidase (Pnc1) | Nicotine deamidase | PNC1 | PNC1_YEAST |
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| Type: | Enzyme |
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| Mol. Mass.: | 24990.99 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | P53184 |
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| Residue: | 216 |
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| Sequence: | MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF
AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV
DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY
KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK
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| BDBM92850 |
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| n/a |
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| Name | BDBM92850 |
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| Synonyms: | Nicotinamidase Inhibitor, 17 |
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| Type | Small molecule |
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| Emp. Form. | C6H4BrNO |
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| Mol. Mass. | 186.006 |
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| SMILES | Brc1cncc(C=O)c1 |
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| Structure | 
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