| Reaction Details |
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 | Report a problem with these data |
| Target | Isochorismatase domain-containing protein |
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| Ligand | BDBM92851 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | GDH-Coupled Nicotinamidase Assay |
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| Ki | 140±20 nM |
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| Citation |  French, JB; Cen, Y; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism. Biochemistry49:10421-39 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isochorismatase domain-containing protein |
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| Name: | Isochorismatase domain-containing protein |
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| Synonyms: | Nicotinamidase (CePNC2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36083.31 |
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| Organism: | Caenorhabditis elegans |
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| Description: | Q7YTI0 |
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| Residue: | 316 |
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| Sequence: | MGVVQNEQDIREKMKNELISLVNEIDLIPELDRLLDDFIENKTWNEDTQELFTRVVLKPF
TTLRTSLLVVDFQNDFVTGSLSIKEGDAEQDPLEALPHVNNLLENLNWNMIVYTQDWHPS
NHISFFEHARNPDRELAPEDKSRKLRPFDIVRFVKPVSTIQVLYPSHCIQGGWGSQLHLG
LQRIDGAHYIKKGADVYVDAYSAFSDNCGIKQSELEMLLRKNDINAVIGCGLAYDICVMH
TLKDASKHGFLTCIVKSGSKGLSSLKMDEANKMFQKRGVAIIDDEMAQLISRREAFPIEW
IRLLVHQAQSELHGKK
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| BDBM92851 |
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| n/a |
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| Name | BDBM92851 |
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| Synonyms: | Nicotinamidase Inhibitor, 18 |
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| Type | Small molecule |
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| Emp. Form. | C7H7NO2 |
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| Mol. Mass. | 137.136 |
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| SMILES | COc1cncc(C=O)c1 |
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| Structure | 
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