Reaction Details |
| Report a problem with these data |
Target | Peptidyl-prolyl cis-trans isomerase B |
---|
Ligand | BDBM92920 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | PPIase Assay |
---|
pH | 7.8±n/a |
---|
Temperature | 278.15±n/a K |
---|
Ki | 6.3e+4± 1.2e+4 nM |
---|
Comments | extracted |
---|
Citation | Daum, S; Schumann, M; Mathea, S; Aumüller, T; Balsley, MA; Constant, SL; de Lacroix, BF; Kruska, F; Braun, M; Schiene-Fischer, C Isoform-specific inhibition of cyclophilins. Biochemistry48:6268-77 (2009) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Peptidyl-prolyl cis-trans isomerase B |
---|
Name: | Peptidyl-prolyl cis-trans isomerase B |
Synonyms: | CYP-S1 | CYPB | Cyclophilin B | Cyclophilin B (CypB) | PPIB | PPIB_HUMAN | PPIase | Peptidyl-prolyl cis-trans isomerase B | Rotamase | S-cyclophilin | SCYLP |
Type: | Protein |
Mol. Mass.: | 23751.82 |
Organism: | Homo sapiens (Human) |
Description: | P23284 |
Residue: | 216 |
Sequence: | MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRV
IFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYG
ERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVR
KVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE
|
|
|
BDBM92920 |
---|
n/a |
---|
Name | BDBM92920 |
Synonyms: | Benzofuranone, 9 |
Type | Small molecule |
Emp. Form. | C17H14O3 |
Mol. Mass. | 266.2913 |
SMILES | COc1ccc2OC3(Cc4ccccc4C3)C(=O)c2c1 |
Structure |
|