| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C alpha type |
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| Ligand | BDBM92977 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mixed Micelle Assay |
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| pH | 7.5±0 |
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| Temperature | 303.15±0 K |
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| IC50 | 1.64e+5±n/a nM |
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| Citation |  Bottega, R; Epand, RM Inhibition of protein kinase C by cationic amphiphiles. Biochemistry31:9025-30 (1992) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein kinase C alpha type |
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| Name: | Protein kinase C alpha type |
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| Synonyms: | KPCA_RAT | Pkca | Prkca | Protein kinase C (PKC) | Protein kinase C alpha | Protein kinase C alpha type |
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| Type: | Protein |
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| Mol. Mass.: | 76797.67 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P05696 |
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| Residue: | 672 |
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| Sequence: | MADVYPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN
PQFVHPILQSAV
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| BDBM92977 |
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| n/a |
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| Name | BDBM92977 |
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| Synonyms: | Amphiphile, XII |
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| Type | Small molecule |
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| Emp. Form. | C35H64N4O5 |
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| Mol. Mass. | 620.9054 |
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| SMILES | CC(C)CCCC(N)C1CCN2C3OC=C4CC(CCC4(C)C3CCC12C)OC(=O)CCC(=O)OCC[NH+](C)CC[NH+](C)C |t:14| |
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| Structure | 
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